Frizzled Family Receptor 8 (FZD8) (N-Term) Peptide
FZD8
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN977174
Aperçu rapide pour Frizzled Family Receptor 8 (FZD8) (N-Term) Peptide (ABIN977174)
Antigène
FZD8
(Frizzled Family Receptor 8 (FZD8))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FZD8 antibody (Catalog #: ARP41283_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- FZD8 (Frizzled Family Receptor 8 (FZD8))
-
Sujet
-
FZD8 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Alias Symbols: FZ-8, hFZ8
Protein Interaction Partner: RYK,WNT1,GOPC,LRP5,LRP6,RYK,WNT1,LRP5,LRP6,WNT1
Protein Size: 694 -
Poids moléculaire
- 73 kDa
-
ID gène
- 8325
-
NCBI Accession
- NM_031866, NP_114072
-
UniProt
- Q9H461
Antigène
-
Vous êtes ici:
